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RegenPRP All New Skin Rejuvenation Program

RegenPRP

RegenPRP is an aesthetic treatment that uses the healing potential of the patients own blood to bio-stimulate skin cells. Using the richness of growth factors contained in RegenPlasma and the process of mesenchymal stem cells stimulation to regenerate and revitalise damaged skin

What is PRP & How Does It Work?

PRP (Platelet-Rich-Plasma) is an autologous therapy in which a patient’s own platelets are concentrated by centrifugation of a blood sample taken at the point of treatment. The Platelet-rich-plasma is then injected back into the patient’s target tissue to stimulate wound repair and tissue regeneration. PRP has been in use for many years in diverse medical fields including orthopaedics, dentistry and chronic wound care. It is now rapidly growing in popularity in aesthetic medicine due to its many scientific and ethical advantages over traditional anti-ageing treatments such as Botulinum toxin.

PRP utilises the body’s natural healing mechanisms to elicit wound repair and tissue regeneration. Platelets are a rich source of growth factors including Platelet Derived Growth Factor (PDGF), Transforming Growth Factor Beta (TGF-ß), Insulin-Like Growth Factor-1 (IGF-1), Epidermal Growth Factor (EGF), Vascular Endothelial Growth Factor (VEGF) and basic Fibroblast Growth Factor (bFGF). During treatment, platelets and plasma are first derived from the patient’s blood sample by centrifugation. The platelets are then activated to release growth factors and the product is ready to use. When injected locally into the patient’s skin, the product stimulates regeneration and rejuvenation. This occurs by multiple mechanisms including stem cell proliferation, epidermal thickening, angiogenesis (increasing the blood supply) and stimulation of dermal collagen and elastin production. In addition to platelets, the plasma component of the product plays an important role in the treatment process and contains many factors essential for cell survival including nutrients, vitamins, hormones, electrolytes and proteins. The plasma proteins include essential molecules for the coagulation process and generation of the fibrin polymer that serves as a scaffold for cell migration, differentiation and proliferation during skin regeneration. Fibrin entraps platelets at the site of action, ensuring the efficient distribution of growth factors. The fibrin gel also exerts direct volumising effects on the patient’s skin.

PRP can be used to treat the tell tale signs of ageing. Fine lines and wrinkles, tired skin and acne scars can all be reduced/improved. Regen are a scientific research company who have developed a protocol and kit for this exact purpose. More information on Regen can be found at www.regenlab.com


FAQ'S

  • What is PRP?

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    PRP (Platelet-rich-plasma) is an autologous therapy – this means that your own cells are used to stimulate the natural regenerative properties of your skin. Since the product is derived from your own blood, it avoids any risk of transmissible infections and other diseases. During treatment, your blood sample is placed into a centrifuge to create the product, consisting of platelets concentrated in plasma. The PRP is then applied into your skin to stimulate rejuvenation. PRP has been in use for many years in diverse medical fields including orthopaedics, dentistry and wound care. It is now rapidly growing in popularity in aesthetic medicine due to its many scientific and ethical advantages over traditional anti-ageing treatments such as Botulinum toxin.

  • What are platelets?

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    Platelets are not actually cells, but small fragments of cells circulating naturally in your blood. They are formed in the bone marrow from large cells called megakaryocytes. Each megakaryocyte gives rise to many thousands of platelets and the platelet concentration in the blood of healthy human beings is 150-400 billion per Litre of blood – so we have a lot of them! Platelets are responsible for blood clotting and they release essential growth factors for wound repair. Recent research has shown that the basic biological processes of wound repair play an important role in skin rejuvenation and our body’s natural anti-ageing mechanisms. PRP uses this technology to enhance your body’s own natural processes.

  • What is plasma?

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    Plasma is the liquid component of blood. It consists of a mixture of essential nutrients including sugars, fats, proteins and salts. The major role of plasma is to transport these nutrients to the body’s cells and tissues, along with transporting red and white blood cells and platelets. It also contains antibodies, clotting substances, hormones and proteins that help maintain the body’s natural fluid balance.

  • How does PRP work?

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    PRP utilises the body’s natural healing mechanisms to stimulate skin rejuvenation. Platelets are a rich source of growth factors that play an essential role in the body’s natural anti-ageing mechanisms. During treatment, platelets and plasma are first derived from your own blood sample by centrifugation. The platelets are then activated to release growth factors and the product is ready to use. When injected locally into your skin, the product stimulates regeneration and rejuvenation. This occurs in a number of different ways including stem cell proliferation, thickening of the epidermis (the top layer of your skin), increased blood supply and stimulation of dermal collagen and elastin production. In addition to platelets, the plasma component of the treatment plays an important role in the treatment process and contains many factors essential for cell survival including nutrients, vitamins, hormones, electrolytes and proteins. The plasma proteins include essential molecules for the generation of a fibrin scaffold that supports cell activity and holds the platelets at the site of treatment, ensuring the efficient distribution of growth factors. The fibrin gel component of PRP also exerts direct volumising effects on your skin.

  • Is PRP a form of stem cell treatment?

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    PRP is not formally classed as a direct stem cell treatment and stem cells do not form part of the injected product. However stem cells play an important role in your body’s response to PRP treatment, since one of the major roles of the growth factors released by the platelets is stem cell activation and proliferation – an important contributory factor in tissue rejuvenation.

  • How long does the treatment take?

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    A single treatment is typically completed within 30-45 minutes.

  • How quickly will I see results?

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    The speed of response varies between individuals due to natural differences in a number of key cellular responses. Some patients will notice a change after the first treatment, and most by the second treatment.

  • How many treatments are needed?

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    An initial course of 3 treatments is usually recommended, with a 30 day interval between each session. Depending on your response to treatment, follow up sessions can then be carried out every 6-12 months. The maximum recommended frequency for treatment is once per month.

  • Which skin areas are suited to PRP treatment?

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    Treatment applications include: forehead lines; frown lines; brow shaping; cheek definition; bunny lines; crow’s feet; eye circle; lip wrinkles; chin creasing; nasolabial folds; mouth frown; accordion lines; marionette lines; jawline; back of the hands and décolleté wrinkles or crease-marked skin.

  • Are there any side-effects such as bruising?

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    • Some bruising can occur as a result of PRP treatment and this varies between individuals.  You can minimise the risk of bruising by avoiding alcohol, exercise and steam rooms for 24 hours before and after treatment.  Some people have found it useful to Arnica tablets (homeopathic tablets purchased over-the-counter) for 2-3 days before treatment.
    • Some individuals may experience heat and superficial tension feelings in the skin. These transitory feelings come from the bio-stimulation process and should disappear within 24 to 36 hours after treatment.
    • In very rare cases in individuals with severe allergenic potential, oedemas can appear following a more significant inflammatory response.

  • Are there any medical conditions that would prevent me from having PRP treatment?

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    You should not have PRP treatment if you suffer from any of the following conditions:

    • Cancer (in particular, cervico-facial cancers not confirmed to be in total remission)
    • The presence of any skin lesions that may be related to abnormal cell proliferation
    • Pregnancy
    • Any active infection (acute or systemic)
    • Allergy to local anaesthetic agents
    • Non-Steroidal Anti-Inflammatory Drug (NSAID) treatment in the last 7-10 days
    • Anti-coagulant therapy (contra-indicated for any transdermal injections)
    • Thyroiditis
    • Autoimmune diseases
    • Blood diseases including thrombocytopenia (low platelet count) andthrombasthenia (decreased platelet function).
    • Blood-borne infectious diseases such as hepatitis.
    • Diabetes: PRP poses an increased risk of infection in diabetes and it is important to pre-warn the patient.  (Note that PRP is commonly used to treat diabetic ulcers).

    Note: smoking may diminish the effectiveness of PRP as lower platelet counts have been reported in smokers compared with non-smokers.

  • What are the benefits of RegenPRP over other PRP products?

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    The unique benefits of RegenPRP over other PRP systems are:

    • RegenPRP is extensively supported by ongoing scientific research.
    • Regulatory compliance: RegenPRP is FDA-approved and CE marked, with a level of compliance unrivalled in the industry.

    Scientific research: RegenLab is a Swiss medical device development and manufacturing company, with a state-of-the-art research laboratory dedicated to tissue repair.  A multidisciplinary scientific team works on the design and development of medical devices for applications in the field of regenerative medicine.  Approximately 100,000 patients were treated with Regen products in 2011, with a 50% predicted increase in 2012.  RegenLab is associated with BioBridge, a foundation dedicated to funding research and ongoing education in regenerative medicine.  RegenLab takes product optimisation seriously.  For example, the company has perfected their method to obtain the optimal concentration of platelets in the PRP product.  This avoids over-saturation with bioactive ingredients which would render the patient’s cells unresponsive to therapy.

    Regulatory compliance: RegenACR® kits are CE approved Class IIb medical devices as defined by the European Directive 93/42/EEC.  In compliance with the Directive, all RegenACR® kit components have been tested for biocompatibility according to the ISO 10993 guidelines (confirming the absence of toxicity, irritation and sensitisation) and are pyrogen-free.  RegenACR® kits provide a closed circuit for the preparation of autologous platelet-rich-plasma, minimising the risk of microbial contamination during the sample preparation and treatment process. The blood collection tubes are manufactured from specialised glass to allow maintenance of a high quality PRP product, and the entire kit is contained within a double sterile pack.  The classification of PRP products as Class IIb medical devices is critical to ensure their safe use, and RegenLab leads the field in achieving this level of approval.

    RegenACR® kits are manufactured in Switzerland by RegenLab, authorised by Swissmedic (the Swiss agency for the authorisation and supervision of therapeutic products).  Following the International Conference of Harmonisation (ICH) in 2003, the same laws and regulatory requirements now apply worldwide.

  • What are the benefits of RegenPRP over other PRP products?

    ± click for info

    The unique benefits of RegenPRP over other PRP systems are:

    • RegenPRP is extensively supported by ongoing scientific research.
    • Regulatory compliance: RegenPRP is FDA-approved and CE marked, with a level of compliance unrivalled in the industry.

    Scientific research: RegenLab is a Swiss medical device development and manufacturing company, with a state-of-the-art research laboratory dedicated to tissue repair.  A multidisciplinary scientific team works on the design and development of medical devices for applications in the field of regenerative medicine.  Approximately 100,000 patients were treated with Regen products in 2011, with a 50% predicted increase in 2012.  RegenLab is associated with BioBridge, a foundation dedicated to funding research and ongoing education in regenerative medicine.  RegenLab takes product optimisation seriously.  For example, the company has perfected their method to obtain the optimal concentration of platelets in the PRP product.  This avoids over-saturation with bioactive ingredients which would render the patient’s cells unresponsive to therapy.

    Regulatory compliance: RegenACR® kits are CE approved Class IIb medical devices as defined by the European Directive 93/42/EEC.  In compliance with the Directive, all RegenACR® kit components have been tested for biocompatibility according to the ISO 10993 guidelines (confirming the absence of toxicity, irritation and sensitisation) and are pyrogen-free.  RegenACR® kits provide a closed circuit for the preparation of autologous platelet-rich-plasma, minimising the risk of microbial contamination during the sample preparation and treatment process. The blood collection tubes are manufactured from specialised glass to allow maintenance of a high quality PRP product, and the entire kit is contained within a double sterile pack.  The classification of PRP products as Class IIb medical devices is critical to ensure their safe use, and RegenLab leads the field in achieving this level of approval.

    RegenACR® kits are manufactured in Switzerland by RegenLab, authorised by Swissmedic (the Swiss agency for the authorisation and supervision of therapeutic products).  Following the International Conference of Harmonisation (ICH) in 2003, the same laws and regulatory requirements now apply worldwide.

  • How is PRP different from Botulinum toxin and dermal fillers?

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    Botulinum toxin is a muscle relaxant that prevents or reduces lines and wrinkles by relaxing the muscles of the skin.  Botulinum toxin has no regenerative effect on the skin.  Each manufactured batch of Botulinum toxin is tested on animals and this is an ethical concern for many people.  A rare side effect is over-relaxation of the muscle, resulting in eye- or mouth-droop and difficulty swallowing.

    Dermal fillers are frequently used to correct scarring, wrinkles and other depressions in the skin.  They are ideal for gently softening lines and wrinkles, smoothing out smile lines, defining cheek bones and creating fuller lips.  Some fillers are specifically designed to help hydrate dry skin.  They are made from hyaluronic acid, a naturally occurring substance in the body that degrades over time.  Hyaluronic acid is a major component of the skin’s extracellular matrix, contributing significantly to cell proliferation and migration.  Therefore, in contrast to Botulinum toxin, dermal fillers have mild regenerative effects on the skin.  The side effects of fillers are lumps, migration of product, granuloma formulation, infection, risk of embolism and necrosis.  These side effects can be avoided through use of correct technique.

    PRP is different from both Botulinum toxin and dermal fillers, as it works by autologous biostimulation – using your bodys own growth factors to stimulate the natural regenerative processes of the skin.  The autologous nature of the product means that it is inherently free from any transmissible disease or infection.  Since the treatment is prepared on-site from your own cells, no animal testing of treatment sample is required.  PRP does not give the instant and sometimes dramatic results seen with Botulinum toxin and dermal fillers, but if you are conscious about your internal health and favour natural treatments, PRP provides considerable benefits.  Since PRP treatment triggers the regenerative cascade your skin, the results continue to improve with time.  PRP slows down the ageing process through a wide range of beneficial effects including stem cell proliferation, epidermal thickening, increased blood supply and stimulation of dermal collagen and elastin production.  The technology therefore harnesses the benefits of the latest anti-ageing research.

  • Can PRP be used in conjunction with other ant-ageing treatments?

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    Yes, PRP can be used in conjunction with most other anti-ageing treatments including dermal fillers, muscle relaxant injections (Botulinum toxin), laser and light therapies, ultrasound technologies, skin chemical peels and microdermabrasion. PRP can enhance the effectiveness of other treatments. A two week gap is advised between PRP and alternative treatments.


Full Cost to be confirmed at initial consultation.

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